Midwest Casserole–seasoned beef, potatoes and vegetables all in one dish! Make it in your Instant Pot or slow cooker.

Midwest Casserole
This is a good old fashioned meal that I adapted to the Instant Pot or Crockpot. It’s got meat and potatoes and veggies all in one pot with a bit of melty cheese to finish it off. There is lots of flavor. My family loved this meal. It was easy to clean up too which is always a bonus. Enjoy!
Ingredients/Substitution Ideas
- Lean ground beef–or ground turkey
- Dry minced onion–or ½ cup fresh chopped onion
- Kosher salt
- Black pepper
- Garlic powder
- Smoked paprika
- Beef broth–or chicken broth
- Red potatoes–or peeled russet potatoes
- Frozen mixed vegetables–mine had corn, beans, peas and carrots
- Butter
- Tomato sauce
- Sharp cheddar cheese–or another type of cheese like colby jack
Steps
Turn Instant Pot to saute setting. When display says HOT add in the beef and break it up. Add in the onion, salt, pepper, garlic powder and paprika. Brown for 5 minutes.

Pour in the broth and scrape bottom of pot so that nothing is sticking. Turn off Instant Pot.
Evenly add in the potatoes and then lightly sprinkle with a pinch of salt and pepper. Add in the vegetables and the butter and tomato sauce. Don’t stir.

Cover Instant Pot and secure the lid. Make sure valve is set to sealing. Set the manual/pressure cook button to 3 minutes. When time is up let pot sit for 5 minutes and then move valve to venting. Remove the lid.

Stir.

Sprinkle on the cheese and let it melt.

Serve and enjoy!

Notes/Tips
- Serve with green salad and a dinner roll.
- This recipe is gluten free. You can make this recipe dairy free by leaving out the cheddar.
- I used my 6 quart Instant Pot*. You can also make this in a 3 or 8 quart pot.
- Store leftovers in an airtight container* in the refrigerator for up to 5 days or in the freezer for up to 3 months.
- Other recipes you can make with red potatoes are Holy Moly Soup and No Politics Casserole.
Did you know you can filter the recipes on my website to search by meat type, IP or Crockpot, low carb, gluten free, etc.? Use the filter to find exactly what you are looking for.


Midwest Casserole
- Prep Time: 20 minutes
- Cook Time: 3 minutes (plus 5 minute NPR)
- Total Time: 23 minutes
- Yield: 4–6 servings 1x
Description
Seasoned beef, potatoes and vegetables all in one dish! Make it in your Instant Pot or slow cooker.
Ingredients
- 1 pound lean ground beef
- 1 Tbsp dry minced onion
- 1 tsp kosher salt
- 1/2 tsp black pepper
- 1 tsp garlic powder
- 1/4 tsp smoked paprika
- 1/2 cup beef broth
- 1 pound red potatoes, cut into 1/2 inch cubes
- Salt and pepper
- 1 (10 oz) package frozen mixed vegetables
- 1 Tbsp butter
- 1 (8 oz) can tomato sauce
- 1/2 cup shredded cheddar cheese
Instructions
Instant Pot Instructions:
- Turn Instant Pot to saute setting. When display says HOT add in the beef and break it up. Add in the onion, salt, pepper, garlic powder and paprika. Brown for 5 minutes.
- Pour in the broth and scrape bottom of pot so that nothing is sticking. Turn off Instant Pot.
- Evenly add in the potatoes and then lightly sprinkle with a pinch of salt and pepper. Add in the vegetables and the butter and tomato sauce. Don’t stir.
- Cover Instant Pot and secure the lid. Make sure valve is set to sealing. Set the manual/pressure cook button to 3 minutes. When time is up let pot sit for 5 minutes and then move valve to venting. Remove the lid.
- Stir. Sprinkle on the cheese and let it melt. Serve and enjoy!
Slow Cooker Instructions:
- Heat a pan over medium high heat. Add in the beef and break it up. Add in the onion, salt, pepper, garlic powder and paprika. Brown for 5 minutes. Add to the slow cooker.
- Stir in the broth, potatoes, vegetables, butter and tomato sauce. Lightly sprinkle with a pinch of salt and pepper.
- Cover and cook on low for 3 hours.
- Stir. Sprinkle on the cheese and let it melt. Serve and enjoy!
- Category: Beef
- Method: Instant Pot

More beef and potato recipes…
Time Machine Casserole
An old fashioned meat and potatoes casserole that’s been updated for cooking in your Instant Pot.
Family Feud Casserole
Ground beef, potatoes, green beans, bacon and cheese made in your Instant Pot. A family favorite that may cause a family fight on who gets the last bite.
Stay Away Casserole
Browned beef cubes with potatoes, creamy sauce and cheese made in the Instant Pot.
*Karen Petersen is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com.




Made the recipe for slow cooker. Turned out great! Thanks!
Awesome! thanks for the review!
I made a similar version of this the other day. I used chicken instead of beef, I put in mixed vegetables and rice instead of potatoes, I added diced tomatoes, chopped onions and used tomato sauce because I didn’t have chicken broth and I added water to make it 6 cups liquid. I used seasoned salt, black pepper, garlic, poultry seasoning and crushed red pepper. It turned out pretty good for having to use only what I had.
Sounds like a good version!