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April 28, 2026

5 Ingredient Mexican Casserole

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5 Ingredient Mexican Casserole–an easy 5-ingredient dinner made with tender chicken, tortillas, refried beans and enchilada sauce for a family-friendly meal. Make it in the oven or the slow cooker.

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5 Ingredient Mexican Casserole

5 Ingredient Mexican Casserole

This is one of those recipes that makes life just a bit easier. I love how it comes together with only 5 main ingredients (not counting oil, salt, and pepper) but still tastes great! The chicken gets coated in enchilada sauce and creamy refried beans, and then everything bakes up with melty cheese and soft tortillas layered throughout. If you want to make it faster, try using rotisserie chicken.

Ingredients/Substitution Ideas

  • Olive oil–or avocado oil
  • Boneless skinless chicken breasts–or boneless skinless chicken thighs
  • Kosher salt
  • Black pepper
  • Enchilada sauce–green or red
  • Refried beans
  • Tortillas–or corn tortillas
  • Sharp cheddar cheese–or Monterey Jack or Mexican blend cheese

Steps

Heat oven to 350° F. Spray a 9×13 inch baking dish with non-stick cooking spray.

Heat a large pan over medium high heat. Add in the oil and swirl around. Add in the chicken, sprinkle it with salt and pepper and cook until no longer pink in the middle.

Stir in the enchilada sauce and refried beans, until smooth. Turn off the heat.

Layer half of the chicken mixture, half of the tortillas and half of the cheddar twice in the 9×13 inch baking dish. 

Bake for 30 minutes. Let sit for 5 minutes. Serve and enjoy!

5 Ingredient Mexican Casserole

Notes/Tips

  • Serve with a side salad, chips and salsa, or some Spanish rice.
  • This recipe can be gluten free if you use corn tortillas instead of flour tortillas.
  • Want to save time? Use rotisserie chicken and skip the sauté step.
  • I used 5 large flour tortillas. If you use corn tortillas I would use 8-10.
  • For extra flavor, stir in a can of diced green chiles or a sprinkle of taco seasoning.
  • Store leftovers in an airtight container* in the refrigerator for up to 4 days. Freezing it is okay but the tortillas kind of turn mushy.
  • Other recipes you can make with refried beans are Greg’s Taco Lasagna and Slow Cooker Chicken Enchilada Soup.
Did you know you can filter the recipes on my website to search by meat type, IP or Crockpot, low carb, gluten free, etc.? Use the filter to find exactly what you are looking for. 

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5 Ingredient Mexican Casserole
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5 Ingredient Mexican Casserole


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  • Author: 365 Days of Slow and Pressure Cooking
  • Prep Time: 25 minutes
  • Cook Time: 30 minutes
  • Total Time: 55 minutes
  • Yield: 6 servings 1x
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Description

An easy 5-ingredient dinner made with tender chicken, tortillas, refried beans and enchilada sauce for a family-friendly meal. Make it in the oven or the slow cooker.


Ingredients

Scale
  • 1 Tbsp olive oil
  • 1 1/2 pounds boneless skinless chicken breasts, cut into 1 inch cubes
  • 1/2 tsp kosher salt
  • 1/2 tsp black pepper
  • 1 (10 oz) can green or red enchilada sauce
  • 1 (16 oz) can refried beans
  • 5 large tortillas, cut into 1 inch squares (I use a pizza cutter)
  • 2 cups shredded sharp cheddar cheese

Instructions

Oven Instructions:

  1. Heat oven to 350° F. Spray a 9×13 inch baking dish with non-stick cooking spray.
  2. Heat a large pan over medium high heat. Add in the oil and swirl around. Add in the chicken and sprinkle with salt and pepper. Cook until no longer pink in the middle.
  3. Stir in the enchilada sauce and refried beans, until smooth. Turn off the heat.
  4. Layer half of the chicken mixture, half of the tortillas and half of the cheddar twice in the 9×13 inch baking dish. 
  5. Bake for 30 minutes. Let sit for 5 minutes. Serve and enjoy!

Slow Cooker Instructions:

  1. Spray inside of slow cooker with non-stick cooking spray.
  2. Heat a large pan over medium high heat. Add in the oil and swirl around. Add in the chicken and sprinkle with salt and pepper. Cook until no longer pink in the middle. 
  3. Stir in the enchilada sauce and refried beans, until smooth. Turn off the heat.
  4. Layer half of the chicken mixture, half of the tortillas and half of the cheddar twice in the slow cooker.
  5. Cover and cook on high for 2 hours. Serve and enjoy!
  • Category: Chicken
  • Method: Stove and Oven

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Instant Pot Bubble Up Enchiladas

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Grandma Kay’s Enchiladas (Instant Pot, Crockpot or Oven)

Grandma Kay’s Enchiladas can be made in the Instant Pot, Crockpot or Oven. They are filled with chicken and green chiles and then smothered in a creamy and cheesy green chile enchilada sauce. 

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Instant Pot Loaded Beef Enchiladas Soup

A fast and easy soup recipe with ground beef, beans, corn, enchilada sauce, tomatoes and green chiles. It’s topped with tortilla strips, cheddar cheese, sour cream and cilantro for a beef enchilada in a bowl meal. 

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Joanna Gaines’ Chicken Enchiladas

Joanna Gaines’ Chicken Enchiladas can be made in the Instant Pot or the Crockpot. Chicken, cheese and green chiles are rolled up in flour tortillas and then topped with a creamy green enchilada sauce. Finally the enchiladas are topped with mozzarella cheese. These enchiladas don’t look the prettiest but they taste AMAZING. Comfort food to the max. 

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*Karen Petersen is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com.

Leave a Comment Filed Under: All Recipes, Beans, Can Be Gluten Free, Chicken, Other Methods, Slow Cooker

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Hi, I’m Karen. I know that dinner time can be less than relaxing. Busy schedules and cranky kids and a hundred other things can lead to weariness when it comes to putting dinner on the table. I can help! I make homemade, family-friendly slow cooker and Instant Pot dinners and share the recipes with you.

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